Secondary immunodeficiency are formed under the influence of the environment, are much more common than primary and are manifested in chronic purulent-inflammatory diseases of the skin, the upper respiratory tract, lung, genitourinary system, the gastrointestinal tract, and others organs.
The causes of secondary immunodeficiency:
1. Infectious agents - viral, bacterial, parasitic, fungal diseases which damage, inhibit the cells, alter the immune response. An example is HIV.
2. Non-infectious factors - methods of treatment that suppress the immune system, malnutrition, metabolism, intoxication, any serious diseases (cancer, heart disease, lung, liver), stress conditions (operative trauma, anesthesia, heavy physical exertion), burns, adverse ecological environment (chemical factors, polluting air, water, food, physical factors - ultraviolet light, radiation, etc.).
Violations during child bearing, causing immunopathology in the unborn child
- Genetic factor;
- Toxicosis of the first and second half of pregnancy (immune conflicts mother of the fetus, of which the fruit comes with serious lesions);
- The threat of spontaneous abortion (miscarriage);
- Various diseases of the pregnant woman and application of medical products;
- Smoking, drinking, taking narcotic substances;
- Work or life of the pregnant woman in the conditions associated with hazards (computer work, paint work), especially in the first half of pregnancy, when there is a very rapid formation of the fetus;